Morphologic and physiologic retinal degeneration induced by intravenous delivery of vitamin A dimers in the leporid retina
نویسندگان
چکیده
منابع مشابه
Morphological and physiological retinal degeneration induced by intravenous delivery of vitamin A dimers in rabbits
The eye uses vitamin A as a cofactor to sense light and, during this process, some vitamin A molecules dimerize, forming vitamin A dimers. A striking chemical signature of retinas undergoing degeneration in major eye diseases such as age-related macular degeneration (AMD) and Stargardt disease is the accumulation of these dimers in the retinal pigment epithelium (RPE) and Bruch's membrane (BM)....
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ژورنال
عنوان ژورنال: Disease Models & Mechanisms
سال: 2014
ISSN: 1754-8411,1754-8403
DOI: 10.1242/dmm.017194